I haven't seen the new episode yet, but The Anchoress has -- and her readers are aghast that she's honoring the show that disrespected the Virgin Mary.
MORE: From Captain Ed.
YET MORE: I have seen the episode now. It's quite careful in the way it deals with Muslim sensibilities. Muhammad is not depicted (though he has been in old episodes). The show isn't about how Muslims overreact, but about how Americans overreact. And the spoof of "The Family Guy" looks as though it would be quite amusing to someone familiar with "The Family Guy."